ALAT Recommendations for the Use of Respiratory Vaccines Evidence-Based Clinical Practice Guideline

Main Article Content

Rafael Rodriguez
https://orcid.org/0000-0003-2320-958X
Francisco Arancibia
Mark Cohen
https://orcid.org/0000-0003-0222-3817
Lydiana Ávila
https://orcid.org/0000-0002-9579-1591
Adrián Rendón
https://orcid.org/0000-0001-8973-4024
Lorena Noriega
https://orcid.org/0000-0003-1806-9797

Abstract

Introduction: Respiratory infections are the leading cause of respiratory disease-related mortality worldwide. Infections caused by Streptococcus pneumoniae, influenza virus, Bordetella pertussis, SARS-CoV-2 and Respiratory Syncytial Virus (RSV) now have safe and effective vaccines available.


This document represents a Clinical Practice Guideline (CPG) by the Latin American Thoracic Association (ALAT), developed through the initiative of the departments of infectious diseases and pediatrics, with the goal of establishing recommendations on respiratory vaccines using the available evidence.


Method: A guideline development group was established, composed of five lead physicians responsible for the overall project. Five working subgroups were created, one for each vaccine, involving invited experts in adult pulmonology, pediatrics, and infectious diseases, who formulated clinical questions. A group of expert methodologists then transformed these clinical questions into PICO questions, with nine questions selected using the DELPHI method. The GRADE (Grading of Recommendations Assessment, Development and Evaluation) system was then used to assess the available evidence.


Results: Recommendations were obtained for the adult and pediatric populations for pneumococcal, influenza, pertussis, COVID-19 and Respiratory Syncytial Virus vaccines based on PICO questions. Additionally, recommendations based on narrative questions related to the use of respiratory vaccines in populations with chronic respiratory diseases such as asthma, COPD, and pulmonary fibrosis were included. 

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How to Cite
Rodriguez, R., Arancibia , F., Cohen, M., Ávila, L., Rendón, A., & Noriega, L. (2024). ALAT Recommendations for the Use of Respiratory Vaccines: Evidence-Based Clinical Practice Guideline. Respirar, 16(3), 203–233. https://doi.org/10.55720/respirar.16.3.1
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