Recomendaciones para el manejo de la Enfermedad Pulmonar Post Tuberculosis Departamento de Tuberculosis ALAT

Contenido principal del artículo

Sandra Inwentarz
https://orcid.org/0000-0002-7526-1577
Giovanni Battista Migliori
https://orcid.org/0000-0002-7526-1577
Laura Lagrutta
https://orcid.org/0000-0003-0927-4385
Fernanda Bornengo
https://orcid.org/0009-0006-0161-6677
Jimena Lujan Falco
https://orcid.org/0009-0007-2026-3907
Yanet de Sosa Márquez
https://orcid.org/0009-0004-0603-0769
Carolina Baroni
https://orcid.org/0000-0002-2722-2194
Manuel Eduardo Espinoza Hernandez
https://orcid.org/0000-0002-5847-5303
Carlos Peña Martinetti
https://orcid.org/0000-0002-7573-6501
Marisa Vescovo
https://orcid.org/0000-0002-3716-5349

Resumen

Introducción: Los esfuerzos de la lucha contra la tuberculosis (TB) se centran habitualmente en un diagnóstico precoz y un tratamiento eficaz y oportuno para romper la cadena de transmisión de Mycobacterium tuberculosis. Sin embargo, en los últimos años, coincidiendo con la asociación sindemica TB/COVID-19, han aparecido cada vez más evidencias sobre las graves secuelas clínicas, funcionales y psicosociales que puede ocasionar la TB, condición que se ha definido como Enfermedad Pulmonar Post-Tuberculosis (PTLD). Aproximadamente, un tercio de los pacientes que sobreviven a la TB se enfrentan a esto, incluyendo síntomas respiratorios persistentes con exacerbaciones episódicas, insuficiencia respiratoria crónica, trastornos emocionales y desafíos psicosociales que impactan negativamente en la calidad de vida relacionada con la salud, y enfrentan un alto costo catastrófico.


Objetivo: Proporcionar un modelo compartido, orientador y científicamente válido para diagnosticar, evaluar y tratar en forma oportuna a los pacientes con PTLD (prevención, diagnóstico, tratamiento y posible rehabilitación).


Metodología: Es una investigación documental que incluye revisiones sistemáticas, meta-análisis- estudios observacionales y de las directrices existentes en los últimos años al respecto, sumado a una evaluación por expertos en el tema, con el propósito de adaptarlas a las condiciones locales de cada pais latino-americano.


Conclusiones: Considerando la carga mundial, particularmente, latinoamericana de TB, y la carga estimada de la PTLD, se considera urgente el desarrollo de un consenso sobre este tema. Creemos que las recomendaciones de ALAT proporcionarán la base para la formulación y adopción de directrices nacionales para el manejo del PTLD en América Latina.

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Inwentarz, S. ., Migliori, G. B., Lagrutta, L., Bornengo, F. ., Falco, J. L., de Sosa Márquez, Y. ., Baroni, C., Espinoza Hernandez, M. E. ., Peña Martinetti, C. ., & Vescovo, M. (2024). Recomendaciones para el manejo de la Enfermedad Pulmonar Post Tuberculosis: Departamento de Tuberculosis ALAT. Respirar, 16(3), 271–288. https://doi.org/10.55720/respirar.16.3.6
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