Recomendaciones ALAT para el uso de vacunas respiratorias Guía de práctica clínica basada en evidencias.

Contenido principal del artículo

Rafael Rodriguez
https://orcid.org/0000-0003-2320-958X
Francisco Arancibia
Mark Cohen
https://orcid.org/0000-0003-0222-3817
Lydiana Ávila
https://orcid.org/0000-0002-9579-1591
Adrián Rendón
https://orcid.org/0000-0001-8973-4024
Lorena Noriega-Aguirre
https://orcid.org/0000-0003-1806-9797

Resumen

Introducción: Las infecciones respiratorias son las enfermedades respiratorias con mayor mortalidad en el mundo. Las causadas por Streptococcus pneumoniae, virus de influenza, Bordetella pertussis, SARS-CoV-2 y el Virus Sincitial Respiratorio, cuentan hoy día con vacunas seguras y efectivas. Este documento representa una guía de práctica clínica (GPC) de la Asociación Latinoamericana del Tórax (ALAT), elaborada por iniciativa de los departamentos de enfermedades infecciosas y pediatría, con el objetivo de establecer recomendaciones sobre vacunas respiratorias, utilizando la evidencia disponible.


Método: Se estableció un grupo de desarrollo de las guías conformado por un grupo de cinco médicos responsables globales del proyecto, se crearon cinco subgrupos de trabajo, uno por cada vacuna, con expertos neumólogos de adulto, pediatras e infectólogos invitados, que generaron preguntas clínicas.  Se trabajó con un grupo de expertos metodólogos que transformaron preguntas clínicas en preguntas PICO, seleccionándose nueve preguntas por método DELPHI. Luego, se utilizó el sistema GRADE (Grading of Recommendations Assessment, Development and Evaluation) para evaluar la  evidencia disponible.


Resultados: Se obtuvieron recomendaciones para población adulta y pediátrica de las vacunas de neumococo, influenza, tos ferina, COVI-19 y Virus Respiratorio Sincitial basadas en preguntas PICO.


También se agregaron recomendaciones basadas en preguntas narrativas relacionadas al uso de vacunas respiratorias en población con enfermedades respiratorias crónicas como asma, EPOC y fibrosis pulmonar.

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Rodriguez, R., Arancibia , F., Cohen, M., Ávila, L., Rendón, A., & Noriega-Aguirre, L. (2024). Recomendaciones ALAT para el uso de vacunas respiratorias: Guía de práctica clínica basada en evidencias. Respirar, 16(3), 203–233. https://doi.org/10.55720/respirar.16.3.1
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