Changes in Stress Index and Peak Inspiratory Pressure after Pneumoperitoneum in Laparoscopic Cholecystectomy
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Abstract
Background: Pneumoperitoneum in laparoscopic surgery affects both the cardiovascular and respiratory system, but it is not fully understood whether adjustments in ventilatory settings could potentially minimize impaired compliance and higher peak inspiratory pressures during these surgical procedures.
Methods: We collected data from patients who underwent elective laparoscopic cholecystectomy and while using the same ventilatory parameters, recorded changes in airway peak inspiratory pressure and stress index before and after pneumoperitoneum. Continuous normally distributed data was expressed as mean±standard deviation and differences between baseline and post pneumoperitoneum were analysed using a paired student’s t test (statistical software packages Prism Graphpad® and SPSS® for Mac). A p value of 0.05 was considered significant.
Results: We studied 18 patients and found a change in stress index (from a baseline value of 1 to a <1, p<0.05) after pneumoperitoneum and an increase in peak airway pressures (mmHg) (Ppeak 14.9±0.7 vs 18.1±1.4 respectively, p <0.005).
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