Reference Values for the Six-Minute Walk Test in a Healthy Adult Population in Ecuador

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María Belén Noboa Sevilla
https://orcid.org/0000-0003-0535-0299
Washington David Arias-Calvache
https://orcid.org/0000-0003-0589-7796
Santiago Cadena-Mosquera
https://orcid.org/0000-0002-7541-8087
Rodrigo Torres-Castro
Matías Otto-Yáñez
https://orcid.org/0000-0001-5784-275X

Abstract

Introduction: The six-minute walk test (6MWT) is a widely used assessment tool for evaluating functional capacity in various clinical settings. In Ecuador, however, no population-specific reference equations are currently available.


Objective: To establish reference values and a predictive equation for the 6MWT in healthy Ecuadorian adults.


Methods: Cross-sectional study of adults aged 20–60 years recruited in three cities at 2,225–2,850 m above sea level. Anthropometric and physiological variables were recorded before/after the 6MWT. A multiple linear regression model (enter method) was used to predict six-minute walk distance (6MWD). Consistency with external equations was assessed using ICC; agreement was examined with Bland–Altman plots and Lin’s concordance correlation coefficient. 


Results: We analyzed 303 healthy participants. Median 6MWD was 649 m [597–692]. The final equation included age, height, and sex (R² = 0.304). The lower limit of normality was defined as the predicted value − 94.9 m. The Osses and Casanova equations showed low consistency and a lack of absolute agreement with the observed values. 


Conclusion: This study provides reference values and a population-specific predictive equation for healthy Ecuadorian adults. These findings may support the use of functional assessment in patients with respiratory diseases.

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Reference Values for the Six-Minute Walk Test in a Healthy Adult Population in Ecuador. (2026). Respirar, 18(1). https://doi.org/10.55720/

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