Correlation of Cardiac Output by Blood Gas Analysis and Echocardiography in Critical Care Medicine at very High Altitude
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Abstract
Introduction: Cardiac output (CO) is a marker to determine the global hemodynamic state. Its determination by Fick's principle has been used by invasive and non-invasive methods such as simple blood gas analysis (GA), the latter has been displaced by more modern methods. Transthoracic echocardiography (TTE) is a validated and reliable method to determine CO. The objective of this study is to determine if there is a linear relationship between the CO by GA through theoretical formulas and the GC obtained by TEE.
Material and Methods: Observational, descriptive, cross-sectional and single-center study. Patients admitted to the Adult Intensive Care Unit of the Hospital del Norte in the city of El Alto at 4,150 meters above sea level were included. The data was tabulated in Excel. Normality tests, Bravais-Pearson correlation, Bland-Altman test were performed with the SPSS Statistics v 29 program; the White test for heteroskedasticity was performed in XLSTAT. The Hospital Bioethics committee approved the study protocol.
Results: The Bravais-Pearson r coefficient was 0.60 (95% CI: 0.18 to 0.82; p value 0.007). This relationship increased when we used the formula proposed by this study with r 0.64 (95% CI: 0.23 to 0.84; p value 0.003). We found a linear relationship between stroke volume (SV) and arterial O2 concentration (CaO2) with r 0.8 (95% CI: 0.5 to 0.9; p 0.001).
Conclusion: There was a linear correlation of CO by both methods in patients.
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